Course Description:
Recorded at AIHce EXP 2023

Recent legislation directs the EPA to include workers in chemical exposure risk evaluations as well as the general population and susceptible subpopulations. Drawing on the recently completed risk evaluation for trichloroethylene (TCE), this session will discuss: 1) how chemicals are evaluated under the new TSCA process; 2) useful features of interest to IH practitioners; 3) the tools used for assessing chemical exposures and risks; 4) COUs and susceptible subpopulations; 5) the margin of exposure (MOE); 6) central tendency and high-end measured or modeled exposure estimates; 7) glove and respiratory protection factors for workers; 8) assessing uncertainties with an exposure scenario; and 9) determining risk of injury from evaluation results. Beyond its application for TSCA risk management, the EPA's Risk Evaluation Procedure can provide IH practitioners with a framework for assessing a range of workplace scenarios, if used with an understanding of its limitations and assumptions.

Learning Outcomes:
Upon completion of the session, the participant will be able to:

• Recognize the terminology used in the EPA's Risk Evaluation Procedure.
• Calculate the central tendency and high-end exposure estimates using measured or modeled data for each COU.
• Evaluate MOE and uncertainty for a scenario using exposure estimates and a Benchmark Dose (BMD) level.
• Describe how the results from the MOE calculation relate to risk of injury.
• Explain limitations of this approach when evaluating real-world exposures and risks in the workplace.

Contact Hours:
1

Presentation Date:
05/24/2023

Presenters:
John Lowe, CIH
Pamela Williams, ScD, CIH