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Benchmark Dose Modeling for Carcinogenic Risk Assessment (AIHce EXP 2023 OnDemand)



Course Description:
Recorded at AIHce EXP 2023

Benchmark dose method is one of the most famous quantitative approaches available for toxicological risks prediction. Occupational health professionals would benefit from better understanding of the benchmark dose approach and its applicability to carcinogenic risk assessment. The session will lead the audience through several examples showing: 1) how benchmark dose calculations approximate dose–response data on carcinogenic response; 2) estimations of risks in the situations when more complex models are not warranted; 3) carbon nanotubes, amosite asbestos, and glyphosate exposure assessments; and
4) the software for benchmark dose calculations based on the toxicological and human epidemiological data points

Learning Outcomes:
Upon completion of the session, the participant will be able to:

• Discuss the applicability of benchmark dose modeling to health risk assessments.
• Select software for benchmark dose calculations.
• Calculate cancer risk from carbon nanotubes, asbestos, and glyphosate exposures.
• Recognize the limitations and uncertainties in benchmark dose calculations.

Contact Hours:
1

Presentation Date:
05/22/2023

Presenters:
Eric Rasmuson, MHS, MS, DABT, CIH
Andrey Korchevskiy, PhD, DABT, CIH