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Beyond Banding Estimating Health-Based Limits for Data Poor Chemicals PDC Recording



Course Description:
Recorded in June 2020, this course will strengthen your ability to establish relevant health-based limits and evaluate your workplaces.

Because of the industrial and commercial use of thousands of chemicals, IH professionals and others are frequently tasked with developing risk assessments for substances without a quantitative occupational exposure limit (OEL). A significant effort to fill this gap has focused on OEL derivation and occupational exposure banding (OEB) methods.

However, for many chemicals in commerce, these methods are not viable because there is little or no data available on the chemicals' health hazards. This PDC will: a) build on the foundations of the hierarchy of OELs; b) teach how to navigate existing data resources and relevant tools for developing health-based occupational limits for chemicals that lack toxicology data; and c) address three methods (read-across, a threshold of toxicological concern (TTC), hazard correlation).

Learning Outcomes:
Upon completion, students will be able to:

  • Identify key resources for finding hazard data relevant to deriving OELs.
  • Apply current frameworks for read-across to select chemical analogs for a chemical.
  • Develop a health-based quantitative limit using correlation methods and the Threshold of Toxicological Concern method.
Contact Hours:
3.5 Hours

Learning Levels:
Intermediate

Course Authors:
Anders Abelmann, MS, PhD, CIH
William Cyrs, MS, CIH
Andrew Maier, PhD, CIH, DABT, FAIHA
Rachel Zisook, MS, CIH